The ClinGen v4 Pilot Calculator is intended for piloting and testing the DRAFT ACMG/AMP/CAP/ClinGen Standards for Sequence Variant Classification v4.0 framework.

Please provide your feedback on classifying variants using the SVC v4 framework through the appropriate Feedback Forms available in the Main Navigation Menu.

Detailed guidance for using each of the code workflows and additional resources for the pilot are available in the Guidance sections of the Main Navigation Menu.

For questions related to the v4 framework, assistance with its use, or questions about the pilot process please contact us through email.

Should you encounter any issues regarding the data displayed, or other problems with the calculator tool, please let us know through the Software Help Desk.